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IMPRS / Graduate Schools

caesar seminar series

19.01.2017, 11 am

Prof. Tansu Celikel
Radboud University, Nijmegen
"Sensory consequences of adaptive motor control"

Further information

Caesar is a Neuroscience research institute associated with the Max Planck Society. Caesar’s research is interdisciplinary with scientists from various research areas working together on the topics of cellular signal processing and the neural foundations of behavior. 

News

How cortical circuits keep the balance in imbalance

Model of the neuronal networks in sensory cortex

Bonn, 15.12.2016. Cortical neurons receive thousands of excitatory and inhibitory signals, both from local and long-range circuits. To keep the neurons in a functional dynamic range, near their firing threshold - for example, to detect new sensory stimuli - the excitatory and inhibitory signals have to be balanced. Substantial perturbation of this balance between excitatory and inhibitory signals results in inadequate responses of the neuron to stimuli - either the neuron remains completely quiescent or it is active in an uncontrolled way, as during an epileptic seizure. Commonly, models of the cortex assume that circuit architecture is homogeneous. For example, the number of excitatory and inhibitory connections to each neuron is assumed to be highly coordinated. This allows each neuron to remain in balance between excitation and inhibition. However, anatomical studies have now shown that this is not the case! Excitatory and inhibitory connections do not follow uniform patterns. The functional effect of such structural heterogeneity has been investigated by scientists of the group "In Silico Brain Sciences" headed by Marcel Oberlaender at research center caesar in Bonn in collaboration with a group of scientists headed by Haim Sompolinsky, and was supported by the Max-Planck-Hebrew Center, the Max Planck Society, and the Hebrew University in Jerusalem. [more]


New independent research group at caesar

Bonn, 01.12.2016. The Max Planck Society has granted funding to Elmar Behrmann, research group leader at the caesar research center, to enable him to set up a free-floating Max Planck Research Group. The funding awarded will total approx. 2 million euros for the next five years. [more]